Pixilated prison surveillance video shows the very moments Andrew Ortega was being strangled behind the locked door of his downstate jail cell.

Two teachers now share a special bond, after one volunteered to make a life-saving donation to her friend's family in their time of need.

A woman known as the "Ketamine Queen," charged with selling Matthew Perry the drug that killed him, agreed to plead guilty Monday.

Work is ramping up on a new CTA train station at State and Lake streets in the Loop.

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Chicago Public Schools officials said a gun was found at Whitney Young High School Monday, as students returned for their first day back after summer break.

Some tenants in a suburban Milwaukee apartment building were trapped Sunday night after a balcony collapsed.

Anguished Pakistanis searched remote areas for bodies swept away by weekend flash floods as the death toll reached 277 on Monday.

"The case was never about the evidence." Amanda Knox speaks to ABC News Studios about her wrongful conviction and the aftermath in "Search for the Truth: The Amanda Knox Story," airing Friday at 8p|7c on ABC and streaming the next day on Hulu.

Crews are out in Mount Prospect Monday surveying severe storm damage at an apartment complex.

The Texas measles outbreak that sickened 762 people since late January is over, state health officials said Monday.

Erik and Lyle Menendez's fight for freedom will continue this week when the brothers face a parole board, separately.

Sunday in the Cemetery features talks, workshops and tours. The experience shows guests the end-of-life process through diverse perspectives.

A real-life criminal took inspiration from the fictional crime show, "You." ABC News Studios covers all the details in "Stalking Samantha: 13 Years of Terror," streaming on Hulu.

Chicago Mayor Brandon Johnson was among those attending a groundbreaking Monday morning for a new concourse at O'Hare International Airport.

Louisiana sued the online gaming platform Roblox on Thursday, alleging it allowed sexual predators to "thrive, unite, hunt and victimize kids."

A teenage boy was shot to death in the west suburbs on Saturday night, police said. A suspect was later taken into custody.

Ismael Mario Zambada Garca, the alleged former drug lord and top leader of the Sinaloa cartel known as El Mayo, is set to plead guilty to federal charges next week, court documents show.

Chicago fire crews responded to a building collapse Monday morning on the city's South Side.

The Chicago area could experience severe storms Monday evening on a day when many students head back to school.

There are unwelcome house guests, and then there's this -- a mountain lion strutting through the front door of a La Verne, California home.

Amanda Puck with Mariano's joined ABC7 with some easy lunch ideas for your kids that are budget friendly too.

Democratic lawmakers from Texas just arrived at O'Hare Monday to head back to the Lone Star State.

Air Canada suspended plans to restart operations Sunday after the union representing 10,000 flight attendants said it will defy a return to work order.

"You're dealing with a major hurricane. The intensity is fluctuating. It's a dangerous hurricane in any event," Richard Pasch of the National Hurricane Center said.