The City of Festus, Missouri has reached a "framework" agreement to move forward with a proposed $6 billion data center, despite widespread opposition from local residents.

A memorable season from the St. Louis University (SLU) Billikens' men's basketball comes to an end in the second round of the NCAA March Madness tournament, following a 95-72 loss to Michigan.

A St. Louis County woman has admitted to filing false claims in a $174,000 home healthcare fraud scheme.

Officers detained 23 juveniles on the first night of a weekend-long youth curfew in St. Louis' Downtown and Downtown West neighborhoods, police say.

The St. Louis University (SLU) Billikens, fresh off a dominant first-round March Madness win, are back in action Saturday against the Michigan Wolverines, a battle of the No. 1 vs. No. 9 seeds.

ST. LOUIS (AP) Malik Reneau scored 24 points, Tre Donaldson hit a couple of big baskets down the stretch, and seventh-seeded Miami pulled away late for a 80-66 victory over No. 10 seed Missouri on Friday night in the first round of the NCAA Tournament. Donaldson finished with 17 points, and Shelton Henderson had 15 [...]

Residents in south St. Louis County are calling for safety improvements on Kingston Drive following a string of high-speed crashes, including a two-car collision that damaged a home earlier this week.

St. Louis Lambert International Airport is reporting security wait times of seven minutes or less as a partial government shutdown creates hour-long delays at major airports nationwide. While TSA workers remain unpaid due to a funding failure in the U.S. Senate, Lambert has emerged as an outlier to the staffing-related chaos seen in other cities.

Fans supporting eight different mens basketball teams are in St. Louis this weekend as part of the annual March Madness.

The excitement of the NCAA Tournament is in full swing in St. Louis, where the Enterprise Center has become a hub for basketball fans during the first two rounds of March Madness.

The director of St. Louis Countys Minority and Women-Owned Business Enterprise program has filed a lawsuit against the county, saying he was suspended for speaking out about what he believed to be poor management and structural conflicts within the program.

Pam Hupps grandmotherly like presence almost seemed friendly as she walked into a St. Charles County courtroom. The now 67-year-old Hupp could face the death penalty if convicted of her current murder charge.

The city of St. Louis began a new phase of tornado recovery Friday by demolishing two heavily damaged homes, 10 months after a devastating storm moved through the area.

St. Louis is forecast for some record-breaking warmth this weekend, with the potential to hit temperatures that we haven't seen at this time of year in over 100 years.

The Missouri Tigers (No. 10 seed) are set to take on the Miami Hurricanes (No. 14 seed) on Friday in their first-round March Madness matchup.

A Missouri appeals court is reviewing whether a St. Louis gun-storage rule goes too far or not far enough. This comes after a lower court struck down a city ordinance last year that required firearms in unattended vehicle to be locked and hidden.

Missouri health officials have confirmed the state's first two cases of a severe mpox strain known as Clade I mpox.

In a season full of statement wins and rising expectations for the St. Louis Billikens men's basketball program, Robbie Avila has emerged not only as one of the most compelling figures in St. Louis sports, but across all of college basketball.

The Missouri Tigers are set to open their NCAA March Madness run in St. Louis on Friday against the Miami Hurricanes, a highly-anticipated clash between No. 7 and No. 10 seeds with Mizzou as the lower-seeded underdog.

Police are searching for a man who robbed FCB Bank in O'Fallon on Friday morning and are asking anyone with information to contact the O'Fallon Police Department.

Chuck Norris, a martial artist and actor known for his appearances in The Way of the Dragon and Walker, Texas Ranger, has died, his family announced Friday.

The Enterprise Center in St. Louis will host four NCAA men's basketball tournament games on Friday, featuring a late-night matchup between the in-state Missouri Tigers and the University of Miami.

St. Louis University's men's basketball team celebrated a record-breaking 102-77 victory over the Georgia Bulldogs in the first round of the NCAA Tournament, marking their first win since 2014 and setting a new school record with 29 victories in a single season.

ST. LOUIS - An amplifying heat dome over the western United States will transfer that warmth eastward through the weekend. The first official weekend of spring will be more summer-like with some record high temperatures in jeopardy. A cold front will halt the warming trend by Sunday night and drop temperatures back into the 50s [...]

The Florissant Police Department announced its officers led a coordinated, multi-jurisdictional operation resulting in the arrest Tuesday of a group of teens who are accused of being involved in various violent crimes across the St. Louis area.