Three generations of a Florida family, including two young children, were killed in a Plant City shooting spree spanning two locations, police say.

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Joint Task Force Southern Spear conducted a lethal strike on a vessel in the Caribbean tied to suspected drug trafficking, killing two people.

Researchers at MCRI are working toward treatments for KAND, a rare neurodegenerative disorder often described as a form of childhood dementia.

The Fox News Lifestyle Newsletter brings you trending stories on family, travel, food, neighbors helping neighbors, pets, autos, military veterans, heroes, faith and American values.

Oklahoma police say a shooting at an unsanctioned party promoted on social media near Arcadia Lake injured nearly two dozen people on Sunday night.

"Sopranos" star Jamie-Lynn Sigler opens up in her memoir about discovering her ex-husband allegedly stole hundreds of thousands of dollars from her.

Elizabeth Hurley reveals she's farming in Tennessee after linking up with Billy Ray Cyrus, signaling a possible end to her legendary bikini era.

NYC Mayor Mamdani's city-run grocery store proposal draws pushback from East Harlem small business owners who say the area is already well served.

House Democrats' campaign arm faces progressive backlash after endorsing a centrist over a far-left challenger in a key California battleground race.

Stunning viral footage shows a grizzly bear fighting a wolf over the remains of a dead animal in a river, proving size matters in the wild kingdom.

Celebrate Cinco de Mayo with Guy Fieri's favorite taco spots across the U.S., as seen on "Diners, Drive-Ins & Dives" and featuring bold flavors worth the trip.

The Cubs rallied to beat the Reds on Michael Conforto's walk-off homer after Pete Crow-Armstrong tied the game with a ninth-inning sacrifice fly run.

Stay Free Alberta declared it has enough signatures to trigger a vote on Alberta leaving Canada, with a provincewide ballot possible by October 2025.

John Cena says he will break "history-making news" at WWE Backlash after ending his in-ring career in December with a retirement match against Gunther.

Streaming apps expose more data than most people realize. A VPN can protect your privacy at home and help you access content while traveling abroad.

Hall of Famer Tracy McGrady criticized the Orlando Magic roster after their historic collapse, blowing a 3-1 lead to the Detroit Pistons in round one.

Gerrymandering reshapes political power by letting mapmakers decide how votes are grouped, making some voices count more than others in U.S. elections.

Royal experts compare Meghan Markle to Wallis Simpson but say it's their husbands, Prince Harry and Edward, who deserve scrutiny for their royal exits.

New blood tests measuring p-tau217 levels show promise for predicting Alzheimer's risk years before symptoms appear, though validation is still needed.

LeBron James hyped up Caitlin Clark on Instagram ahead of her third WNBA season as the Indiana Fever prepare to open Saturday against the Dallas Wings.

As the affordability crisis hits Americans, a new coalition of labor and lawmakers pushes a federal $25 minimum wage mandate amid job loss warnings.

Republican Sen. Lindsey Graham of South Carolina floated the idea of further U.S. military attacks against the Islamic Republic of Iran.

Ben Stiller attended the Met Gala in New York Knicks colors and predicted "Knicks in six" while skipping their playoff game against the Philadelphia 76ers.