Cancer diagnostics company Exact Sciences directly or indirectly contributes between $6 billion and $7 billion annually to the states economy, or more than 1.7% of the gross state product.

The No. 1 “best” city to live in America is a Chicago suburb, according to a new ranking. School and community ratings and review site Niche released its “2026 Best Places to Live in America” report Tuesday, analyzing more than 230 cities and 18,000 locations nationwide. The rankings, editors said, use “a blend of comprehensive public data and ...

"All I can say is that the discussions have been very positive and productive, and hopefully headed in the right direction," said Senate Majority Leader John Thune, R-S.D.

After more than decade apart, a dog that was stolen from a Philadelphia backyard was reunited with his family in an emotional and heartwarming moment.

One suspect was injured and in custody after a police chase in Elmwood Park Tuesday morning, police said.

Democrats are pushing new tax-cut plans to ease voters' affordability worries and blunt Republicans' advantage on the issue.

This State Journal editorial ran on March 19, 1976:

AI is driving massive changes, some of which could hurt greater Minnesota.

More details are coming to light in the shooting and killing of 18-year-old Loyola University Chicago freshman Sheridan Gorman, with prosecutors saying the suspect was hiding behind a lighthouse on a pier before he came out and shot her. Jose G. Medina 25, was charged by Chicago police Friday with first-degree murder, attempted first degree murder, ...

A crash involving at least three vehicles occurred Tuesday morning on Route 28 just before the Highland Park Bridge.

Lauren Babbitt and Eva Blatz made the dean’s list at the University of Buffalo for the fall 2025 semester.

The Village Board disagrees on the timeline and also has to decide if it will offer alternatives for those who dont want fluoride.

Owner Tim Lynn hopes to convert it into a pregnancy resource center, veterans housing facility, memory care center, or rehabilitation center for people with mental health or substance abuse issues.

A flight attendant still strapped in her seat survived being thrown from an Air Canada plane that collided with a fire truck at New York’s LaGuardia Airport, her daughter said Monday. It’s a “total miracle, Sarah Lepine told Canadian news station TVA Nouvelles. She said her mother, Solange Tremblay, had multiple fractures to one leg and will ...

Su Casa Pub & Grill, a restaurant in Holmen, has successfully blended classic American diner dishes with authentic Mexican cuisine on their menu, offering something for everyone.

Hmong's Golden Eggrolls has officially opened its new storefront in Onalaska, marking the end of its rental days and the beginning of a new era in a building of its own.

The awards will be presented during the 26th Reaching for Rainbows Pursuit of Excellence scholarship gala on Friday, May 8, at Carthage College.

With election day just a few weeks away, and absentee voting beginning Tuesday, candidates for the La Crosse County board are trying to make the most of their campaign contributions.

Construction could last roughly two years.

A fire left a home in north suburban Lincolnwood damaged Tuesday morning.

A search in northern Indiana grows more desperate by the day.

The Persian New Year, or Nowruz, is normally a joyous time in Iran. But war and economic uncertainty have cast a pall over celebrations.