The compounded GLP-1s are not FDA-approved nor name-brand.

After a breezy end to the workweek, showers and much cooler temperatures move into Denver's weather forecast this weekend.

The heir to the throne made a surprise appearance alongside Cate Blanchett, Hannah Waddingham and Robert Irwin on Graham Nortons BBC chat show.

Rod Steele was, in essence, looking for a sign.

After Pitt’s Week 3 win over Syracuse, Malik Knight got unfortunate news: a shoulder injury he suffered in the game would require surgery.

Pittsburgh Regional Transit will close the Wabash Tunnel permanently Dec. 1, citing its deteriorating infrastructure and the anticipated $43 million it would cost to repair the 123-year-old tunnel.

The Pennsylvania Supreme Court on Friday denied a request by a man facing possible capital punishment to review the Washington County district attorney’s use of the death penalty.

PARIS — After a failed effort at getting sleep during the plane ride over to Dublin for a game last season, T.J. Watt was relieved he slept well during the overnight flight Friday from Pittsburgh to Paris.

The historic campus of St. Mary’s Catholic Church in Lawrenceville is now in the hands of a former pharmacist from Ross who says he’s still working out his plans for the site.

There’s lots of happy talk surrounding next month’s return of a second daily Amtrak Pennsylvanian passenger train that will run between Pittsburgh, Harrisburg and New York City.

North Allegheny (Class 6A), Peters Township (5A), Oakland Catholic (4A), Freeport (3A), Our Lady of the Sacred Heart (2A) and Eden Christian (A) are the No. 1 seeds for the six WPIAL girls volleyball playoff tournaments.

Washington County is now among 43 other counties across Pennsylvania that have recorded confirmed cases of measles amid a growing statewide outbreak.

A homicide charge was held for further prosecution Friday in connection with the death of a Cook man.

Connor Hellebuyck finally has a new home after the Winnipeg Jets granted the three-time Vezina Trophy-winning goaltender’s trade request in a deal that sent him to the New Jersey Devils on Friday.

Springdale Council is taking its first steps toward drafting an ordinance that would help determine where e-bikes can and can’t be used in the borough.

Pittsburgh Steelers fans, it’s time to swap out your beer of choice for a French-inspired mimosa this weekend — it’s almost time for the Paris game.

FORT COLLINS, Colo. — Severe flooding in the Four Corners region on Friday led to water rescues — some from rooftops — and impassable roads, with some residents being told to evacuate low-lying areas of Colorado and New Mexico and others advised to shelter in place until water levels go down.

It’s true every election year, but this cycle especially: It’s the economy, stupid.

An error by staffers in the Westmoreland County Elections Bureau has resulted in 157 voters receiving duplicate mail-in ballots ahead of the Nov. 3 general election.

Here is a weekly look at recent images captured throughout the Alle-­Kiski Valley.

Utility work on the West End Circle — the sprawling juncture of West Carson Street, the West End Bridge and several smaller streets — will lead to traffic restrictions in the area next week.

WPIAL soccer playoffs

The future of the long-shuttered Hotel Saxonburg is apparently one step closer to being revealed.

After being a healthy scratch for four games, Pittsburgh Penguins forward Hendrix Lapierre was afforded the opportunity to rejoin his team’s lineup during Thursday’s 4-0 home win against the Florida Panthers.

A Derry Township man who recently completed a 5-year federal prison sentence for possession of child pornography was ordered Friday to serve up to another 30 years behind bars for the sexual assault of a child.